Physics at nano/micro scales. Biomolecular building blocks. Simplest biomolecular assembly: protein folding. Nanoscale intermolecular interactions important for biology. Protein-ligand binding. Protein higher-order assembly: filaments, networks. ... Protein filaments and motility. DNA, RNA and their assembly assisted by proteins. Viral capsid assembly. Lipid assembly into micelles, bilayers. Lipid-protein co-assembly in membranes. Lipid and polymer structures useful in medicine. Targeted delivery of drugs, genes by nano/micro structures. Cellular assembly in the eye, in insect wings. Cellular assembly at surfaces: gecko feet, duck feathers. Cellular assembly in the presence of crystals: biomineralization.

This course will focus on developing a fundamental understanding of the sources of air pollution and subsequent control. By the end of the course, students will be able to communicate federal and state air pollution policies, identify sources ... of air pollutants and strategies to classify and mitigate emissions. Students will also be able to identify critical air pollutants including sulfur, nitrogen and carbon containing species, photochemical oxidants, halogen containing compounds and air toxics. In addition, the dispersion and transport of pollutants will be discussed; thus the vertical profile, vertical mixing, and temperature and meteorological effects will also be discussed. Students will develop chemical kinetic expressions to describe atmospheric chemistry, in particular the photo stationary state to describe basic VOC-NOx interactions and their impact on ozone formation

The course emphasizes the application of fundamental chemical engineering principles (mass and energy balances, thermodynamics, kinetics, dispersion, mass transfer) to air quality engineering and control. While a differential equations based ... approach is needed for some topics, there will be considerable emphasis on scaling behavior and dimensional analysis and the design of models applied to atmospheric systems.

This course is for upper level undergraduates and early graduate students interested in the scientific challenges of electrochemical power sources. The lecture will start from the fundamental electrochemistry, and thermodynamics and kinetics ... of electrode process, with emphasis on electroanalytical techniques and advanced electrochemical power sources including batteries, fuel cells and supercapacitors.

The emphasis of the class is on developing a conceptual understanding of the device physics and manufacturing processes of crystalline and thin-film photovoltaic cells, and to develop elementary computational skills necessary to quantify solar ... cell efficiency. The class material includes detailed, system-level energy balances necessary to understand how solar energy fits into the complete energy generation, conversion, and storage picture. Quantitative comparisons of PV technology to solar chemical conversion processes and biofuels are made.

The state-of-the-art in metabolic engineering, with a focus on the analysis and engineering of metabolic pathways through (chemical) engineering principles, will be covered. Topics covered include: (1) overview of biochemistry and metabolism; ... (2) metabolic flux analysis and isotope labeling illustrated with examples from the recent scientific literature; (3) technologies for engineering metabolic pathways; (4) metabolic control analysis and pathway regulation; (5) applications of metabolic engineering to synthesis of biofuels and therapeutics; (6) specialized and related subjects such as protein engineering and synthetic biology.

Also listed as BIOE 689N. Physics at nano/micro scales. Biomolecular building blocks. Simplest biomolecular assembly: protein folding. Nanoscale intermolecular interactions important for biology. Protein-ligand binding. Protein higher-order ... assembly: filaments, networks. Protein filaments and motility. DNA, RNA and their assembly assisted by proteins. Viral capsid assembly. Lipid assembly into micelles, bilayers. Lipid-protein co-assembly in membranes. Lipid and polymer structures useful in medicine. Targeted delivery of drugs, genes by nano/micro structures. Cellular assembly in the eye, in insect wings. Cellular assembly at surfaces: gecko feet, duck feathers. Cellular assembly in the presence of crystals: biomineralization.

Statistical mechanics will be introduced to give the fundamental background for atomic to mesoscale molecular modeling. Classical atomic-level simulations methods (Monte Carlo and Molecular Dynamics) and the procedures to develop intra- and ... intermolecular potentials will be covered. This course will also discuss the theory and application of coarse-grained molecular simulations, mesoscale simulations and other modern simulation techniques. A broad range of applications will be included throughout the semester, e.g., phase behavior of small molecules, kinetics, and biophysics.

This course will address thermodyamics issues associated with such emerging technologies as bio-membrane and gene engineering, micro-reactor chemistry and microcapsule drug delivery, micro-fluids and porous media, nanoparticles and nanostructures, ... supercritical extraction and artificial organs. Self-organized criticality, thermodynamics of pattern formation and fractals, finite-size and fluctuation thermodynamics, critical phenomena in soft-matter materials, such as complex fluids, are examples of the topics to be addressed in this course. ENCH 648W: Transport Phenomena in Small and Biological Systems Interdisciplinary course primarily for senior undergraduate and graduate students from engineering or science departments. The course's main goal is to make the students familiar with the fundamental physics and modeling of transport phenomena in small and biological systems, and their current scientific and engineering utilization in microfluidics, nanofluidics and biological systems.

A review of the fundamental principles involved in the design of engineered tissues and organs. Both biological and engineering fundamentals will be considered. Specific tissue systems will be emphasized at the end of the course.

Multiphase systems for the transport and processing of emulsions (immiscible liquids), slurries (solids in liquids) and gassed liquids exhibit a variety of phenomena that occur on different length and time scales. For instance, the pressure ... and/or power required to process an emulsion or solid suspension depend on flow behavior on the vessel scale while the size of emulsion drops and the solids distribution depend on phenomena that occur on the particle/drop scale. In this course we examine a variety of topics that can be brought to bear on the analysis of multi-scale and multiphase flows. Fundamentals will be supported by examples from the chemical, petrochemical, food, personal care pharmaceutical and biomedical process industries.

NanoParticles (NA) ( < 100 nm), and their science and technology play an important role in nature and industry. From air quality standards, nuclear reactor safety, inhalation therapy, workplace exposure, global climate change, to counterterrorism, ... aerosols play a central role in our environment. On the industrial side, NA plays an integral part of reinforcing fillers, pigments and catalysts, and the new emerging field of nanotechnology, they are the building blocks to new materials, which encompass, electronic, photonic and magnetic devices, and bio and chemical sensors.

Advanced topics to include use of a digital computer for mathematical modeling of the dynamics of biological systems; separation techniques for heat sensitive biologically active materials; and transport phenomena in biological systems. ...
Prerequisite: ENCH482. Or permission of ENGR-Chemical & Biomolecular Engineering department; and permission of instructor.

Advanced topics in polymerization kinetics, reactor design and analysis; addition and step-growth polymerization; homogeneous and heterogeneous polymerization; photopolymerization; reactor dynamics; optimal operation and control of industrial ... polymerization reactors.
Prerequisite: ENCH640; or permission of instructor.

Energy & The Environment
Thermal, chemical, and biological processes for conversion of wastes (primarily solid and liquid) to reduce environmental impact and increase recovery of useful energy resources. Emphasis on solid wastes and their composition. Identification ... of pollution products and their control.
Prerequisites: Must have completed undergraduate courses in thermodynamics and heat transfer.

Energy & The Environment
The fundamental methodology for analyzing environmental risk is described with examples for selected applications. Key elements of the environmental risk methodology include: (1) source term and release characterization, (2) migration of ... contaminants in various media, (3) exposure assessment, (4) dose-response evaluation, (5) risk characterization, and (6) risk management. Also included will be an introduction to uncertainty analysis and environmental laws and regulations. It is intended to provide students with the basic skills and knowledge needed to manage, evaluate, or perform environmental risk assessments and risk analyses.